| Title | Tetrode Recording from the Hippocampus of Behaving Mice Coupled with Four-Point-Irradiation Closed-Loop Optogenetics: A Technique to Study the Contribution of Hippocampal SWR Events to Learning |
| Author | Dámaris K. Rangel Guerrero,1 James G. Donnett,2 Jozsef Csicsvari,1 and Krisztián A. Kovács1 |
| Affiliation(s) | 1 Institute of Science and Technology, Klosterneuburg 3400, Austria
2 Axona Ltd, St Albans AL3 6PA, United Kingdom |
| Published | eNeuro. 2018 Jul-Aug; 5(4): ENEURO.0087-18.2018. doi: [10.1523/ENEURO.0087-18.2018] |
| Keyword | rotary joint |
| Snippet | ..via a low-friction rotatory joint (Prizmatix). |
| Abstract | With the advent of optogenetics, it became possible to change the activity of a targeted population of neurons in a temporally controlled manner. To combine the advantages of 60-channel in vivo tetrode recording and laser-based optogenetics, we have developed a closed-loop recording system that allows for the actual electrophysiological signal to be used as a trigger for the laser light mediating the optogenetic intervention. .... |
