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Fiberoptics for Optogenetics for in-vivo and in-vitro stimulation

Introduction

Prizmatix provides a full range solution to the optogenetics in vivo and in vitro fiber optics. Made of silica or polymer fibers, the high NA fibers are assembled to fit any research set-up with various combinations of connectors, ferrules, core diameters and lengths.

    Fiberoptics for Optogenetics

In-vivo fibers - example

This is a Y-shaped fiber for simultaneous in-vivo stimulation of two hemispheres in behaving animals. Two high NA flexible polymer fibers are accommodated in an FC/PC connector, connected to the output port of a rotary joint. The two fiber branches are terminated with ferrules to connect to the fiber cannulae implanted in the animal's head.

Rotary-Joint-fibers-cannulas-for-dual-hemisphere-activation


 In-vitro fiber - example

This is a single fiber with a thin stainless steel tip at its distal end. A high NA 200μm silica fiber is protruding from the tip for several millimeters The stainless steel tip enables anchoring the fiber to a micromanipulator for precise movement and spatial location control. Yet, since the outer diameter of the stainless steel tip is 3-4 times the core diameter of the fiber, it would have been obscured the image under the microscope. Therefore, we design and build these fibers with the polished bare fiber protruding from the tip for several millimeters, improving the positioning accuracy of the fiber over the target in the brain slice.

Optogenetics-Protruding-Fiber-tip


Optional Parameters

  • Fiber specification:
    • Silica fibers NA 0.53. Core diameters [μm]: 200, 400
    • Silica fibers NA 0.37. Core diameters [μm]: 100
  • Fiber length: as required, usually 1-1.5 meters.
  • Connectors: SMA, FC/PC
  • Number of branches: 1, 2, 3.
  • Stainless steel tip diameter [mm]: 0.5 - 2.0
  • Stainless steel tip length [mm]: 10 - 60
  • Fiber protruding length [mm]: 1 – 10

Please specify parameters while ordering


Additional Optogenetics Toolbox items

Accessories
 

 

 See more info on Prizmatix Optogenetics Toolbox here


 

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