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  Products >   Prizmatix IN-VIVO Optogenetics Toolbox   USA/Canada: +1 (248) 436-8085

Prizmatix In-Vivo Optogenetics Toolbox
for Freely Moving Mammals

From Optogenetics LED light source to cannula and everything in between, Prizmatix can provide all the components necessary for your Optogenetics research – including advice and guidance.

In-vivo optogenetics LED modules starting from single wavelength plug-and-go Optogenetics-LED for neuron activation to multi-wavelength systems for activation and silencing.

  

Prizmatix supplies unique polymer optical fibers for Optogenetics light delivery from LED source to cannulae. These optical fibers have high NA and are extremely flexible and non-brittle. For special cases we can supply armored fibers.

Optogenetics Rotary-Joint has an extremely low friction that enables truly free moving animal experiments.

Prizmatix supplies variety of high NA glass implantable cannulae at custom lengths and core diameter.

Prizmatix Pulser / PulserPlus are programmable TTL pulse generators designed especially for Optogenetics experiments in contrast to general purpose devices aimed at electronics technicians.

In-vivo diagram
  1 Optogenetics LED   2 Fiberoptics/Single/Dual Fiber
  3 Rotary Joint   4 Optogenetics Implantable Cannulae
  5 Pulser   6 Sleeves for Implantable Cannulae

Optogenetics LEDs

  (see [1] on drawing)

The high-power fiber-coupled Prizmatix Optogenetics-LED light source available at Violet, Blue, Green, Yellow, Red and Deep Red wavelengths for activation or silencing of various Optogenetics opsins. The LED can be triggered by a standard TTL signal and the power can be precisely controlled by 10 turn potentiometer or by 0-5V analog signal. Single or Dual independent channels as well as stimulation and silencing by same fiber devices are available.

 

For In-Vitro Optogenetics light sources range
of components and accessories click here

      Optogenetics-LED

      Optogenetics-LED-Dual

      Optogenetics-LED-STSI


Single / Dual Optogenetics Fiber

  (see [2]) on drawing

Prizmatix provides diverse fiber optics solutions for optogenetics in-vivo. Made of silica or polymer, these high NA fibers can be constructed to fit any research set-up with various combinations of connectors, ferrules, core diameters and lengths.
Typical Optogenetics in-vivo fiber optics setup will include fiber patch cord from Optogenetics-LED to Rotary Joint (P/N: Optogenetics-Fiber-1000), fiber to connect the Rotary-Joint to cannula (P/N: Optogenetics-Fiber-500) or dual fiber for bilateral activation (P/N: Optogenetics-Fiber-Dual-500). The later can be optimized for mice (1.25mm ferrule) or to rat (2.5mm ferrule). In some setups this fiber can be produced as Armored fiber with very light and flexible metal sheath.
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Fiberoptics for Optogenetics

  Click pictures to enlarge

Optogenetics Fiber

            Optogenetics Dual Fiber

Armored Optogenetics Fiber

 

         Armored Optogenetics Fiber Dual


Optogenetics Rotary Joint

  (see [3]) on drawing

Watch as Prizmatix's Rotary Joint spins freely for over 30 seconds, benefiting from low torque and friction, with minimal impact on behavior. Prizmatix's Rotary Joint is specially designed for Optogenetics experiments with High NA detachable fibers equipped with FC connectors.

Prizmatix Rotary Joint can be used with single or multiple output fibers simultaneously, enabling concurrent delivery of light to separate areas of the brain without loss of power or brightness. See more..

   Fiber-Optic-Rotary-Joint

Optogenetics Implantable Cannulae

  (see [4] on drawing)

Prizmatix Implantable Fiberoptic Cannulae / Ferrules allow direct light stimulation of certain deep brain regions in living animals. Each Cannula consists of a zirconia ferrule accommodating a high NA Silica/POF fiber, protruding from the zirconia ferrule at the specified length.
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Sleeves for Implantable Cannulae

Prizmatix Sleeves are small ceramic or metal parts that enable proper alignment and connection between the Optogenetics-fiber ferrule and the implant (cannula) ferrule. The Sleeves are available for 1.25 mm diameter (Mice) and 2.5 mm diameter (Rat) cannulae.

     Click picture to enlarge


DIY Cannula Kit

 

       Click picture to enlarge

The Prizmatix DIY Optogenetics implant kit allows you to make your own implantable cannula on demand, whenever you need them. The kit contains everything you need to make cannulae for your experiments.
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DIY Cannula Kit instructions


Pulser

  (see [5] on drawing)

The Pulser device is an easy and inexpensive way to create trains of TTL pulses for Optogenetics activation directly from your computer via USB. Pulser includes all necessary hardware, software and cables.

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Pulser

Pulser for Optogenetics Activation

   See the Pulser in action:

Pulser Windows software:

                            
Pulser Software