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The Prizmatix fiber-coupled Optogenetics-LED modules are specially designed
to provide high power and high brightness light to activate or silence various opsins
in optogenetics experiments with freely moving mammals.
The typical Optogenetics-LED
system comprises Fiber-Coupled Optogenetics-LED, Fiber patch cord, Rotary-Joint (Commutator),
thin flexible Optical-fiber (single or dual branch), Sleave and fiber inplant (Cannula).
This page is a summary of all Prizmatix single channel Optogenetics-LEDs.
Please check also:
Optogenetics-LED-User-Manual
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Key Features
- High Power density (e.g. at Blue >380 mW/mm²) at implant tip following Rotary-Joint and all fiber connections.
- Unique large and powerful LEDs enable bilateral illumination with single LED and rotary joint for significant cost saving and without compromising power at implant tip.
- Extremely low torque LED-compatible Rotary-Joint suitable for even the smallest animals
- Precisely adjustable power by 10 turns potentiometers (separately for each channel)
- Opto-Isolated TTL Inputs for fast switching (separately for each channel)
- Opto-Isolated Analog Inputs for external power control (separately for each channel)
- Instant warm up time. Rise / Fall time <10 μs
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Optogenetics Toolbox for Freely Moving Mammals Experiments |
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Common Optogenetics-LED Colors:
| Opsin |
LED Color |
Peak wavelength range (nm) |
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UV- Violet |
385 - 410 |
ChR2
Channelrhodopsin
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Blue |
450 - 465 |
Arch
Archaerhodopsin |
Green |
515 - 525 |
| ArchT |
Green |
515 - 525 |
| C1V1 |
Green |
515 - 525 |
NpHR
Halorhodopsin
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Lime-Green |
540- 600 |
| eNpHR3.0 |
Orange-Red |
600 - 630 |
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Optical Specifications
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| LED specifications
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Units |
Select LED:
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| Spectrum FWHM |
nm |
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| Optical power data are for optical fiber connected to Optogenetics-LED (suitable for in-vitro or fixed preparate applications): |
| Optical Power from 200μm NA0.66 fiber (1m) (Direct connection) |
mW |
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| Optical Power from 250μm NA0.66 fiber (1m) (Direct connection) |
mW |
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| Optical Power from 500μm NA0.63 fiber (1m) (Direct connection) |
mW |
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| Optical Power from 1000μm NA0.63 fiber (1m) (Direct connection) |
mW |
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| Optical Power and irradiance data for full Optogenetics system including Optogenetics-LED, fiber patch cord, Rotary-Joint, Dual/Single fiber) |
| Optical Power from 200μm cannula |
mW |
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| Optical Power from 250μm cannula |
mW |
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| Optical Power from 500μm cannula |
mW |
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| Irradiance from 200μm cannula |
mW/mm² |
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| | | | Wavelength (nm)
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Electrical Specifications
| Digital modulation input |
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Optically isolated TTL |
| Connector for TTL and Analog input |
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BNC |
| Digital modulation frequency |
Hz |
DC-30000 |
| Rise / Fall time (10% - 90%) |
μs |
<10 |
| Analog input voltage range |
V |
0-5 |
| Input Voltage |
V |
12 |
| Power Adaptor Input |
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85-264 VAC, 47-63Hz,1.5A |
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General Specifications
| Operation temperature range |
°C |
10-35 |
| Storage Temperature range |
°C |
-10-35 |
Operating relative humidity
Non condensing |
% |
<90 |
| Dimensions (L x W x H) |
mm |
197 x 174 x 80 |
| Weight |
g |
750 |
Power Adaptor Dimensions
(L x W x H) |
mm |
175 x 72 x 35 |
| Power Adaptor Weight |
g |
270 |
| Power Adaptor Safety |
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| Fan Noise |
dBA |
28.4 |
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Optional Accessories
For more details on optional accessories please see:
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Prizmatix Rotary Joint is
especially designed for Optogenetics experiments
with High NA fibers equipped with FC connectors.
Rotary Joint very low friction and smooth swivel operation are demonstrated
in this video - showing continuous rotation for over 30 seconds after a
fingertip startup.
The torque required for free movement is very low thus reducing
the Rotary Joint's behavioral effect on freely moving animals.
Prizmatix Rotary Joint can be used with large core input optical fiber connected
to several thin output fibers simultaneously. This allows concurrent delivery of light
to separate areas of the brain without loss of power due to the fiber split.
See more..
Rotary Joint
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Prizmatix Implantable Fiberoptic Cannulae / Ferrules
allow direct light stimulation of certain deep brain regions
in living animals.
Each Cannula consists of a Zirconia ferrule
accommodating a high NA Silica optical fiber, protruding from
the Zirconia ferrule at a desired length.
See more...
Cannula
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Prizmatix provides a full solution to the optogenetics
in vivo and in vitro fiber optics. Made of silica or polymer fibers,
the high NA fibers are assembled to fit any research set-up with various
combinations of connectors, ferrules, core diameters and lengths.
Some examples are Y-shaped fibers for simultaneous in-vivo
stimulation of two hemispheres, and fibers with stainless steel tip
with protruding bare fibers for in-vitro activation of brain
slices under a microscope.
See more
Fiberoptics for Optogenetics
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Prizmatix offers a wide range of standard and
customized multi-mode silica / polymer fibers as well
as ferrules for optogenetics research.
A Y-shaped fiber bundle is especially useful
for activating two brain hemispheres simultaneously:
a 1000μm or 1500μm fiber is coupled to the LED and
connected to one side of the Rotary Joint.
From the Joint’s other side emerge two thin fibers which can
then be connected to two separate ferrules: the light from
the LED is divided equally between the two hemispheres
without any loss of power.
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The Pulser USB to TTL interface box with user friendly software
is an easy way to generate trains of pulses for Optogenetics
activation directly from your computer.
See more..
Pulser
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